Description
Recombinant full-length human CAMK1delta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_153498.
CAMK1delta or Ca2+/calmodulin-dependent kinase I-like kinase (CKLiK) is activated by Ca(2+) and calmodulin and is detected in CD34+-derived neutrophils and eosinophils, as well as in mature peripheral blood granulocytes (1). CAMK1delta exhibits Ca(2+)/CaM-dependent activity that is enhanced in vitro by phosphorylation of its Thr180 by CaM-K kinase (CaM-KK)alpha, consistent with detection of CAMK1D-activating activity in HeLa cells (2)